- Overview
- Description
- Application
- Specifications
- Advantage
- Inquiry
- Related Products
Place of Origin: | China |
Brand Name: | FIRSKY |
Model Number: | 1KG |
Certification: | SGS,ISO 9001 |
Purity: | 99% |
Packaging Details: | Custom aluminum packages,paper boxes,wooden cartons |
Delivery Time: | Tracks available within 3-5 working days after payment received |
Payment Terms: | Escrow,Bank transfer,Western Union,Money Gram,Wise,Crypto currencies |
Supply Ability: | 2000T/Mouth |
Description
β-Amyloid-42, also known as Aβ42, is a peptide that plays a significant role in neurobiology and is associated with Alzheimer's disease. It is a specific form of amyloid-beta peptide, consisting of 42 amino acids. β-Amyloid-42 is derived from the amyloid precursor protein through enzymatic cleavage.
Key Features:
- Alzheimer's Disease Marker: β-Amyloid-42 is closely linked to the development and progression of Alzheimer's disease. Accumulation of β-Amyloid-42 in the brain is a hallmark characteristic of the disease.
- Neurotoxicity: Excessive levels of β-Amyloid-42 can lead to the formation of amyloid plaques, which are implicated in neurodegeneration and cognitive decline.
- Structural Properties: β-Amyloid-42 has a tendency to form aggregates and fibrils, contributing to the pathology of Alzheimer's disease.
Application
Research and Applications:
- Disease Mechanisms: Extensive research is ongoing to understand the role of β-Amyloid-42 in the pathogenesis of Alzheimer's disease and its potential as a therapeutic target.
- Diagnostic Biomarker: β-Amyloid-42 is used in laboratory settings as a biomarker for Alzheimer's disease, aiding in the diagnosis and monitoring of the condition.
- Drug Development: Researchers are exploring interventions that can target β-Amyloid-42, aiming to prevent its accumulation or promote its clearance to potentially slow down or halt the progression of Alzheimer's disease.
Specifications
Product Name: | Amyloid β-Peptide (1-42) (human) |
Synonyms: | Bate-Amyloid(1-42)human; (1-42) (human);AB42, betaamyloid peptide;Amyloid βH-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH;REF DUPL: H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH;Beta-Amyloid (1-42), sodium salt;Β-AMYLOID PEPTIDE (1-42), RAT |
CAS: | 107761-42-2 |
MF: | C203H311N55O60S1 |
MW: | 4514.04 |
storage temp. | -20°C |
solubility | Soluble in ammonium hydroxide, pH >9. Also soluble in DMSO. |
form | Lyophilized |
color | Lyophilized White |
Advantage
1.Firsky (Wuhan) keeps working to provide customers with high-quality products steadily. We have established a sound internal quality management system and are constantly striving to improve quality, reduce deviation and waste.
2.If you have any questions, please feel free to ask questions, we will reply to your questions within 48 hours.
3.If you have any questions after receiving the goods, please feel free to contact us. If the loss is caused by us, we guarantee 100% compensation.